Compounds/Psilocybin

Psilocybin

4-Phosphoryloxy-N,N-dimethyltryptamine

Classic PsychedelicsNaturalClassic Psychedelic (Tryptamine)

Duration

4-6 hours

Onset

20-60 minutes

Peak

1-3 hours

Psilocybin is a naturally occurring psychedelic compound found in over 200 species of mushrooms, most commonly in the Psilocybe genus. It's considered one of the most well-researched and therapeutically promising psychedelics.

⚠️ Safety Information

⚠️ Contraindications

Do not use if any of the following apply to you.

  • History of psychosis or schizophrenia
  • Severe mental health conditions
  • Heart conditions or high blood pressure
  • Pregnancy and breastfeeding
  • Use with certain medications (MAOIs, SSRIs)

Effects

Physical

  • Dilated pupils
  • Changes in heart rate and blood pressure
  • Temperature fluctuations
  • Nausea (especially during onset)
  • Muscle tension or relaxation
  • Yawning and fatigue

Psychological

  • Altered sense of time and space
  • Enhanced empathy and emotional openness
  • Introspective thoughts and self-reflection
  • Mood enhancement or emotional lability
  • Sense of unity and interconnectedness
  • Dissolution of ego boundaries

Visual

  • Enhanced colors and visual acuity
  • Geometric patterns and fractals
  • Breathing or morphing of surfaces
  • Visual distortions and illusions
  • Closed-eye visuals (CEVs)
  • Synesthesia

Therapeutic Potential

Treatment-resistant depression relief
End-of-life anxiety reduction
PTSD symptom improvement
Addiction treatment support
Enhanced creativity and problem-solving
Spiritual and personal growth experiences

Legal Status

Illegal in most countries, decriminalized in some regions

Related Compounds

This is education, not medical advice. Always consult a healthcare professional before making decisions about substance use. Never use illegal substances.

Education and harm reduction only. This is not medical advice. Always consult a healthcare professional. Never use illegal substances.