Muscimol
Amanita muscaria
AtypicalNaturalGABAergic Psychoactive (GABA-A receptor agonist)
Duration
4-10 hours
Onset
30-120 minutes
Peak
2-4 hours
Muscimol is the primary psychoactive compound found in Amanita muscaria (fly agaric) mushrooms. Unlike psilocybin, muscimol acts on GABA receptors, producing dream-like states, altered perception, and unique experiences that differ significantly from classical psychedelics.
⚠️ Safety Information
⚠️ Contraindications
Do not use if any of the following apply to you.
- •Liver disease or hepatic conditions
- •Pregnancy and breastfeeding
- •History of severe mental health conditions
- •Use with alcohol or other depressants
- •Respiratory conditions (due to sedating effects)
Effects
Physical
- •Sedation and muscle relaxation
- •Possible loss of motor coordination
- •Drowsiness and tendency to sleep
- •Altered perception of body size and weight
- •Possible nausea (less common than with psilocybin)
- •Enhanced tactile sensations
Psychological
- •Dream-like states and altered consciousness
- •Possible out-of-body experiences
- •Enhanced introspection and reflection
- •Altered perception of time and space
- •Possible euphoria or mood changes
- •Enhanced connection with nature and folklore
Visual
- •Altered size perception (macropsia/micropsia)
- •Enhanced colors and visual depth
- •Possible mild geometric patterns
- •Dream-like visual experiences
- •Generally less intense visuals than classical psychedelics
Therapeutic Potential
✓Deep relaxation and stress relief
✓Enhanced dream work and lucid dreaming
✓Traditional shamanic and spiritual applications
✓Possible applications for anxiety and insomnia
✓Enhanced creativity and artistic inspiration
✓Connection with folklore and traditional practices
Legal Status
Legal in most jurisdictions
Related Compounds
This is education, not medical advice. Always consult a healthcare professional before making decisions about substance use. Never use illegal substances.